FETAL AND INFANT EFFECTS OF MATERNAL OPIOID USE DURING PREGNANCY: A LITERATURE REVIEW INCLUDING CLINICAL, TOXICOLOGICAL, PHARMACOGENOMIC, AND EPIGENETIC ASPECTS FOR FORENSIC EVALUATION

The two primary classes of opioid substances are morphine and its synthetic derivative, heroin.Opioids can cross the placental barrier, reaching fetal circulation.Therefore, at any gestational age, the fetus is highly exposed to pharmacologically active opioid metabolites and their associated adverse effects.This review AlphaBoot: accelerated conta

The outcome of patients underwent to allogeneic stem cell transplantation (allo- SCT) is closely related to graft versus host disease (GvHD) and graft versus leukemia (GvL) effects which can be mediated by mHAgs.23 mHAgs have been identified and reported to be differently correlated with GVHD or GVL and the aim of this work was develop a method to

Abstract Background Despite several years of implementation, prevention of mother-to-child transmission (PMTCT) programmes in many resource poor settings are failing to reach the majority of HIV positive women.We report on a data driven participatory quality improvement intervention implemented in a high HIV prevalence district in South Africa.Meth

The development and deployment of several wireless and cellular networks mean that users will demand to be always connected as they move around.Mobile nodes will therefore have several interfaces and connections will be seamlessly switched among available networks using vertical handover techniques.Proactive handover mechanisms can be combined with